Corrina Moucheraud, ScD, MPH is an affiliate at the UCLA Center for Health Policy Research. Moucheraud is also an associate professor in the Department of Public Health Policy & Management, and co-director of the Global Center for Implementation Science. 

As a global health researcher and implementation scientist, she seeks to improve outcomes by strengthening health systems and enabling the delivery of effective, equitable health services. Much of Moucheraud’s focus is on meeting the needs of women and young people, particularly in low- and middle-income countries. Moucheraud is currently leading efforts for cervical cancer prevention, including HPV vaccination, in Kenya and Malawi. She also researches HIV & non-communicable disease prevention and treatment internationally and in the U.S.

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Factors Associated With Cervical Cancer Screening: Results From Cross-Sectional Surveys in Kenya and Malawi
Journal Article
Journal Article

Factors Associated With Cervical Cancer Screening: Results From Cross-Sectional Surveys in Kenya and Malawi

Summary: This analysis leverages data collected in 2022–2023 from a national mobile phone-based survey in Kenya and from a household survey conducted in three districts of Malawi. Authors assess whether women’s reported cervical cancer screening history (ever or never screened) was associated with their perceived susceptibility (awareness of cervical cancer risk factors), perceived severity (knowing someone who was affected by cervical cancer), perceived barriers (access to services), perceived benefits (trust in information about cervical cancer prevention), self-efficacy (engagement in other preventive health behaviors), and cues to action (speaking with others about cervical cancer prevention). 

Findings: Ever-screening for cervical cancer was reported by 49.7% of the 736 Kenyan respondents and 42.5% of the 261 Malawian respondents. There were few associations between women’s demographic or socioeconomic characteristics and screening history. The strongest associations were seen for cues to action (women who had spoken about cervical cancer with health workers had 1.88 the adjusted risk ratio for screening in Kenya and 1.89 the adjusted risk in Malawi compared to women who never had these conversations); and for knowing someone who had or who had died due to cervical cancer. In both countries, self-efficacy was also associated with screening, as was perceived severity in both countries (i.e., knowing someone who had, or who had died due to cervical cancer, which was reported by many Kenyan and Malawian respondents). In Kenya, knowledge of cervical cancer risk factors was also associated with women’s screening history, as was access to other preventive health services in Malawi. 

These results suggest promising areas for interventions aiming to increase cervical cancer screening in these contexts: encouraging health workers to discuss screening with eligible women, leveraging women’s peers who have been affected by cervical cancer, and promoting screening during other preventive health services.

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Journal Article
Journal Article

Cost-Effectiveness of Approaches to Cervical Cancer Screening in Malawi: Comparison of Frequencies, Lesion Treatment Techniques, and Risk-Stratified Approaches

Recently updated global guidelines for cervical cancer screening incorporated new technologies-most significantly, the inclusion of Human papillomavirus (HPV) DNA detection as a primary screening test-but leave many implementation decisions at countries' discretion. Authors sought to develop recommendations for Malawi as a test case since it has the second-highest cervical cancer burden globally and high HIV prevalence. They incorporated updated epidemiologic data, the full range of ablation methods recommended, and a more nuanced representation of how HIV status intersects with cervical cancer risk and exposure to screening to model outcomes of different approaches to screening.

Using a Markov model, authors estimated the relative health outcomes and costs of different approaches to cervical cancer screening among Malawian women. The model was parameterized using published data, and focused on comparing "triage" approaches-i.e., lesion treatment (cryotherapy or thermocoagulation) at differing frequencies and varying by HIV status. Health outcomes were quality-adjusted life years (QALYs) and deaths averted.

Findings: Thermocoagulation was more cost-effective than cryotherapy at all screening frequencies. Screening women once per decade would avert substantially more deaths than screening only once per lifetime, at relatively little additional cost. Moreover, at this frequency, it would be advisable to ensure that all women who screen positive receive treatment (rather than investing in further increases in screening frequency): for a similar gain in QALYs, it would cost more than four times as much to implement once-per-5 years screening with only 50% of women treated versus once-per-decade screening with 100% of women treated. Stratified screening schedules by HIV status was found to be an optimal approach.

These results add new evidence about cost-effective approaches to cervical cancer screening in low-income countries. At relatively infrequent screening intervals, if resources are limited, it would be more cost-effective to invest in scaling up thermocoagulation for treatment before increasing the recommended screening frequency. In Malawi or countries in a similar stage of the HIV epidemic, a stratified approach that prioritizes more frequent screening for women living with HIV may be more cost-effective than population-wide recommendations that are HIV status neutral.

Photo of Books
Journal Article
Journal Article

Preventing, but Not Caring for, Adolescent Pregnancies? Disparities in the Quality of Reproductive Health Care in Sub-Saharan Africa

There is concern that adolescents experience worse quality of health care than older women. Authors compare quality of reproductive health services (family planning and antenatal care) for adolescents (<20 years) versus adult women (≥25 years) in four sub-Saharan African countries.

In total, 2,342 family planning visits and 8,600 antenatal care visits were analyzed from Democratic Republic of the Congo, Malawi, Senegal, and Tanzania. Service Provision Assessment surveys include observation of care and client exit interviews. Researchers compare visit content and care satisfaction for adolescents versus adult women aged ≥25.

Findings: Adolescents receive more overall family planning care activities compared to adult women, and 3.76 more discussion activities (e.g., counseling) on average, but significantly fewer discussion activities during antenatal care. However, adolescents' satisfaction with both care types was not significantly different than adult women. These relationships largely persist in country-stratified models, using different model specifications, and when comparing adolescents to women aged ≥20.

Adolescents' family planning visits are similar to, or even slightly more comprehensive than, adult women, but their antenatal visits include fewer recommended care components with particular gaps for activities requiring provider-client dialog. This suggests opportunities for strengthening communication between providers and young women, and improving care across the reproductive health continuum.

Association of HIV Status and Treatment Characteristics with VIA Screening Outcomes in Malawi: A Retrospective Analysis (PLos One)
Journal Article
Journal Article

Association of HIV Status and Treatment Characteristics with VIA Screening Outcomes in Malawi: A Retrospective Analysis (PLos One)

Summary: Although evidence from high-resource settings indicates that women with HIV are at higher risk of acquiring high-risk HPV and developing cervical cancer, data from cervical cancer "screen and treat" programs using visual inspection with acetic acid (VIA) in lower-income countries have found mixed evidence about the association between HIV status and screening outcomes. Moreover, there is limited evidence regarding the effect of HIV-related characteristics (e.g., viral suppression, treatment factors) on screening outcomes in these high HIV burden settings.

This study aimed to evaluate the relationship between HIV status, HIV treatment, and viral suppression with cervical cancer screening outcomes. Data from a "screen and treat" program based at a large, free antiretroviral therapy (ART) clinic in Lilongwe, Malawi was retrospectively analyzed to determine rates of abnormal VIA results and suspected cancer, and coverage of same-day treatment.

Findings: Of 1,405 women receiving first-time VIA screening between 2017–2019, 13 (0.9%) had suspected cancer and 68 (4.8%) had pre-cancerous lesions, of whom 50 (73.5%) received same-day lesion treatment. There was no significant association found between HIV status and screening outcomes.

In this population of women living with HIV with high rates of ART coverage and viral suppression, HIV status was not significantly associated with abnormal cervical cancer screening results. Authors hypothesize that ART treatment and viral suppression may mitigate the elevated risk of cervical cancer for women living with HIV, and they encourage further study on this relationship in high HIV burden settings.

 

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Factors Associated With Cervical Cancer Screening: Results From Cross-Sectional Surveys in Kenya and Malawi
Journal Article
Journal Article

Factors Associated With Cervical Cancer Screening: Results From Cross-Sectional Surveys in Kenya and Malawi

Summary: This analysis leverages data collected in 2022–2023 from a national mobile phone-based survey in Kenya and from a household survey conducted in three districts of Malawi. Authors assess whether women’s reported cervical cancer screening history (ever or never screened) was associated with their perceived susceptibility (awareness of cervical cancer risk factors), perceived severity (knowing someone who was affected by cervical cancer), perceived barriers (access to services), perceived benefits (trust in information about cervical cancer prevention), self-efficacy (engagement in other preventive health behaviors), and cues to action (speaking with others about cervical cancer prevention). 

Findings: Ever-screening for cervical cancer was reported by 49.7% of the 736 Kenyan respondents and 42.5% of the 261 Malawian respondents. There were few associations between women’s demographic or socioeconomic characteristics and screening history. The strongest associations were seen for cues to action (women who had spoken about cervical cancer with health workers had 1.88 the adjusted risk ratio for screening in Kenya and 1.89 the adjusted risk in Malawi compared to women who never had these conversations); and for knowing someone who had or who had died due to cervical cancer. In both countries, self-efficacy was also associated with screening, as was perceived severity in both countries (i.e., knowing someone who had, or who had died due to cervical cancer, which was reported by many Kenyan and Malawian respondents). In Kenya, knowledge of cervical cancer risk factors was also associated with women’s screening history, as was access to other preventive health services in Malawi. 

These results suggest promising areas for interventions aiming to increase cervical cancer screening in these contexts: encouraging health workers to discuss screening with eligible women, leveraging women’s peers who have been affected by cervical cancer, and promoting screening during other preventive health services.

View All Publications

Photo of Books
Journal Article
Journal Article

Cost-Effectiveness of Approaches to Cervical Cancer Screening in Malawi: Comparison of Frequencies, Lesion Treatment Techniques, and Risk-Stratified Approaches

Recently updated global guidelines for cervical cancer screening incorporated new technologies-most significantly, the inclusion of Human papillomavirus (HPV) DNA detection as a primary screening test-but leave many implementation decisions at countries' discretion. Authors sought to develop recommendations for Malawi as a test case since it has the second-highest cervical cancer burden globally and high HIV prevalence. They incorporated updated epidemiologic data, the full range of ablation methods recommended, and a more nuanced representation of how HIV status intersects with cervical cancer risk and exposure to screening to model outcomes of different approaches to screening.

Using a Markov model, authors estimated the relative health outcomes and costs of different approaches to cervical cancer screening among Malawian women. The model was parameterized using published data, and focused on comparing "triage" approaches-i.e., lesion treatment (cryotherapy or thermocoagulation) at differing frequencies and varying by HIV status. Health outcomes were quality-adjusted life years (QALYs) and deaths averted.

Findings: Thermocoagulation was more cost-effective than cryotherapy at all screening frequencies. Screening women once per decade would avert substantially more deaths than screening only once per lifetime, at relatively little additional cost. Moreover, at this frequency, it would be advisable to ensure that all women who screen positive receive treatment (rather than investing in further increases in screening frequency): for a similar gain in QALYs, it would cost more than four times as much to implement once-per-5 years screening with only 50% of women treated versus once-per-decade screening with 100% of women treated. Stratified screening schedules by HIV status was found to be an optimal approach.

These results add new evidence about cost-effective approaches to cervical cancer screening in low-income countries. At relatively infrequent screening intervals, if resources are limited, it would be more cost-effective to invest in scaling up thermocoagulation for treatment before increasing the recommended screening frequency. In Malawi or countries in a similar stage of the HIV epidemic, a stratified approach that prioritizes more frequent screening for women living with HIV may be more cost-effective than population-wide recommendations that are HIV status neutral.

Photo of Books
Journal Article
Journal Article

Preventing, but Not Caring for, Adolescent Pregnancies? Disparities in the Quality of Reproductive Health Care in Sub-Saharan Africa

There is concern that adolescents experience worse quality of health care than older women. Authors compare quality of reproductive health services (family planning and antenatal care) for adolescents (<20 years) versus adult women (≥25 years) in four sub-Saharan African countries.

In total, 2,342 family planning visits and 8,600 antenatal care visits were analyzed from Democratic Republic of the Congo, Malawi, Senegal, and Tanzania. Service Provision Assessment surveys include observation of care and client exit interviews. Researchers compare visit content and care satisfaction for adolescents versus adult women aged ≥25.

Findings: Adolescents receive more overall family planning care activities compared to adult women, and 3.76 more discussion activities (e.g., counseling) on average, but significantly fewer discussion activities during antenatal care. However, adolescents' satisfaction with both care types was not significantly different than adult women. These relationships largely persist in country-stratified models, using different model specifications, and when comparing adolescents to women aged ≥20.

Adolescents' family planning visits are similar to, or even slightly more comprehensive than, adult women, but their antenatal visits include fewer recommended care components with particular gaps for activities requiring provider-client dialog. This suggests opportunities for strengthening communication between providers and young women, and improving care across the reproductive health continuum.

Q&A
Ask the Expert

Three Questions with Corrina Moucheraud on Global Health

CorrinaM Ask the Expert graphic


Corrina Moucheraud, ScD, MPH, a global health policy, systems, and services researcher, has been named an associate center director at the UCLA Center for Health Policy Research (CHPR).

She brings over 15 years of experience in global public health research — focusing on areas including HIV/AIDS, women’s health, malaria, and non-communicable diseases such as hypertension — with projects in many lower-resource countries in sub-Saharan Africa and south Asia. She has been a UCLA CHPR faculty associate for the past five years. In this Ask the Expert Q&A, Moucheraud shares her knowledge on how global health policies can be used to inform U.S. health policies, and the deeper implications underscoring the intersection of these two realms.

Q: Your research projects span the global scale in countries across Africa and Asia. What is the connection between global health policy and U.S. health policy, and how may they inform each other?

​It is increasingly evident that public health is global health — the challenges we face here in the U.S. are inextricably linked to what’s happening in other countries. Of course this was highlighted by the COVID-19 pandemic. Likewise, the questions that I explore in my research, and the methods that I use — such as how to maximize quality and ensure impact while operating with scarce resources and budget constraints — are just as relevant in Lilongwe, Malawi as they are in Los Angeles, California.

I currently have international projects on topics like trust in the health system, cost-effectiveness of cancer screening, vaccine uptake and hesitancy, how bias manifests in health care – and all are timely topics here in the U.S. too. We can also gain insights and be exposed to new ideas from lower-resource settings that may inform policies and programs trans-nationally. For example, I’ve participated in research about HIV treatment models in some high-burden African countries that are really at the forefront of innovation, and have the potential to change the way we think about and deliver care here, too. In addition, given the many global forces that affect public health and U.S. health policy like migration and climate change, just to name two — we must acknowledge the interconnectedness of health across nations. Policymaking, public health research, and health care delivery here in the U.S. is made stronger, more relevant, and more innovative if we can see ourselves as part of “global health.”

Q: Are there any lessons you’ve learned from global projects in improving health care and the health care system in the groups you’ve worked with? If so, what lessons could be incorporated or what programs could be adapted and applied here?

​I’ve been lucky to be involved in global research projects that have clear policy and program implications, including for public health here in the U.S. For example, I recently published a paper in Health Affairs that used data from 144 countries to examine how trust in institutions (governments, doctors, and nurses) is associated with trust in health information from these sources. This provides important insights about who’s the best public health messenger, and how trust might intersect with attitudes toward health care. This is a theme I’m further investigating through work in Kenya (led by UCLA Fielding School of Public Health Associate Professor, May Sudhinaraset) about the association between trust in the health system and health care-seeking, and I see this as having important implications for the U.S., too.

I’m also co-chairing a Working Group within the “Rethinking Malaria in the Context of COVID-19” initiative (a global engagement organized by Harvard University in partnership with the World Health Organization’s Global Malaria Programme) about integrated service delivery for malaria control. Malaria affects the health and well-being of many around the world — and, due to climate change, we will see increasing burden of mosquito-borne diseases in the U.S. Mosquitos do not respect borders, so effectively developing, implementing and leveraging policies for malaria control should be a priority for everyone. The global interconnectedness of people, policies and programs — and our joint responsibility for and engagement in public health — provides ample lessons and opportunities for cross-learnings.

Q: It’s no secret that in the U.S., there are highly diverse states which have many different racial and ethnic groups. What are some of the cultural competency approaches you’ve applied on a global scale and how can they be used to help reach groups here?

​One of my favorite things about being a researcher who collects primary data is always expanding my knowledge about data and measurement. In international projects that I work on, we’re often looking for new ways to measure complex social phenomena — for example, how do you assess someone’s socioeconomic status if they don’t have a paycheck to report on? Researchers who work in diverse settings have to devise innovative and culturally-relevant ways to measure things like this, while maintaining rigor and validity. I think there is a lot to be learned from global scholars about culturally competent measurement for diverse populations. This also has implications for program and policy design, since — as we all know from the California Health Interview Survey (CHIS), the Census, and other population-based surveys — how we ask questions and how we measure things impact resource allocation, policy formulation, and ultimately the lives of individuals and communities.

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Center in the News

Health Affairs In 2021: Editor’s Picks

Two separate studies by UCLA CHPR researchers have been recognized among the top 10 articles in 2021 by the scientific journal Health Affairs:

The Effect Of The Affordable Care Act On Cancer Detection Among The Near-Elderly by Fabian Duarte, Srikanth Kadiyala, Gerald F. Kominski, and Antonia Riveros

News https://www.healthaffairs.org/do/10.1377/forefront.20220113.741473?utm_medium=social&utm_source=twitter&utm_campaign=forefront&utm_content=weil
Center in the News

Public health researchers’ studies make journal’s best of 2021 list

Two separate studies by UCLA Fielding School of Public Health researchers have been recognized among the top 10 articles in 2021 by the scientific journal Health Affairs.

The two UCLA Fielding School articles are:

News https://newsroom.ucla.edu/dept/faculty/fielding-school-researchers-top-10-articles-2021

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