Lack of racial and ethnic diversity in health research negatively impacts generalizability. Authors studied Mexican and Mexican American women's willingness to participate in health research in Oregon, conducting a survey with Mexican-origin Latinas aged 18–49 years. The survey included 22 questions about sociodemographics, health care utilization, whether participants had heard of health research, willingness to participate in health research in the future, and barriers and facilitators to participation.

Findings: Of 500 participants, 41% said that they would be willing to participate in health research, 14% said no, and 45% were unsure. In multivariable analyses, past participation in research and speaking English well were independently associated with willingness to participate. Barriers to participation included language, accessibility, and fear of medical procedures. Facilitators included improving future health care, language, and free medical care. Mexican-origin Latinas in Oregon are willing to participate in health research, but many are unsure. Providing study materials in Spanish is a concrete first step to improve recruitment and promote equity and inclusion.

A Computer-Assisted Telephone Interview (CATI) question in the 2019 California Health Interview Survey (CHIS) was used as basis for this study.